Dashwood Lab

Research Areas

The Dashwood Lab dovetails multiomic, genetic, epigenetic, and immune approaches for precision oncology and cancer prevention. Epigenetic readers, writers, and erasers that reversibly regulate alternative splicing and immune players in the antigen presentation pathway are of current mechanistic interest. Lab members come from academic backgrounds such as biochemistry, cancer biology, genetics, molecular nutrition, oncology, and pharmacology. Research tools encompass primary human colon cancers and patient-matched controls, cultured human colon cancer cells and organoids, preclinical models, and mechanistic studies at the molecular level that are translated to human subjects. Supported by the NCI, NINDS/NIA, and the John S. Dunn Foundation.