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April 2022
Congratulations to Dr. Jiang Chang for receiving the prestigious Robert M. Berne Distinguished Lectureship Award from the American Physiological Society! As the Berne Lectureship awardee, Dr. Chang will present a lecture describing his research at the American Physiological Society Annual Meeting 2023.
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Portrait of Dr. Jiang Chang
Dr. Jiang Chang

March 2021
We have joined X (formerly Twitter)! For quick updates on our latest publications and more, give us a follow here: https://x.com/ChangLabIBT

December 2020
After a trying year full of uncertainty and many changes in the lab, Dr. Chang has earned the Senior Investigator Research Excellence Award 2020 from Texas A&M University College of Medicine. Congratulations!
https://medicine.tamu.edu/research/excellence-award.html

EDGES Award graphic
EDGES Award

September 2020
Dr. Chang has received the Chancellor’s Research Initiative “EDGES” Award from Chancellor John Sharp in recognition of his significant research accomplishments. Congratulations Dr. Chang!
Texas A&M University Announces 2020 EDGES Fellows - Texas A&M Today

 

August 2020
Congratulations to our post-doc, Yuan Dai who won second place in the Academy for Research Excellence (ACRE) Young Investigator Award, 2020 with his virtual presentation titled, “Small GTPase RhoE Fine-tunes Inflammatory Response in Myocardial Infarction”!

Yuan Dai receiving award
Yuan Dai Award Presentation

November 2018
Texas A&M Health Vital Record
Improving Patient Outcomes After Heart Attack

February 2016
American Heart Association Awardees List - Tingli Yang
https://professional.heart.org/idc/groups/ahamah-public/@wcm/@sop/@rsch/documents/downloadable/ucm_432214.pdf

September 2014
American Heart Association Awardees List - Xiangsheng "Sean" Yang
https://my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/@rsch/documents/downloadable/ucm_432239.pdf

July 2014
Pathways to Cardiovascular Therapeutics Program - Xiaojing Yue
http://my.americanheart.org/idc/groups/ahamah-public/@wcm/@sop/@scon/documents/downloadable/ucm_465270.pdf

April 23, 2013
Institute of Biosciences and Technology researchers make connection between genetic defect and congenital hydrocephalus
http://www.hydroassoc.org/docs/PressReleases/IBTPNASPRESSRELEASE.pdf

Awards for Research Excellence by Trainees

  • Xiangsheng Yang
    • 3rd place, 15th Annual Student Research Symposium, Texas A&M Health, College Station, 2012
    • Travel Award, Texas A&M Health, College Station, 2012
    • American Heart Association Postdoc Fellowship Award, 7/1/2013 – 6/30/2015
    • American Heart Association-Basic Cardiovascular Sciences New Investigator Travel Award, Las Vegas, July 2014
    • American Heart Association-Academy for Research Excellence Outstanding Presentation Awards, Chicago, November 2014
  • Yuan Dai
    • 2nd place, Academy for Research Excellence (ACRE) Young Investigator Award, 2020
    • China Scholarship Council Scholarship Award, 9/1/2012 – 8/31/2016
    • Outstanding Young Investigator Award from Academy for Research Excellence, American Heart Association Basic Cardiovascular Sciences 2016 Scientific Sessions: Pathways to Cardiovascular Therapeutics. Phoenix, Arizona, July 18-21
  • Xiaojing Yue
    • China Scholarship Council Scholarship Award, 9/1/2010 – 8/31/2014
    • American Heart Association Cardiovascular Outreach Award, Basic Cardiovascular Sciences Conference, Las Vegas, July 2014
    • 1st place prize in American Heart Association-Basic Cardiovascular Sciences, Academy of Cardiovascular Research Excellence, Chicago, USA, July 2014
  • Tingli Yang
    • American Heart Association Predoctoral Fellowship Award, 1/1/2016 – 12/31/2017
  • Thao Ho
    • 1st Place, Institute of Biosciences and Technology Biotechnology Summer Research Program, August 2019
    • 1st Place, in undergraduate poster competition, American Physician Scientist Association Southern Regional Meeting, September 7, 2019
  • Weijia Luo
    • 1st Place, Young Investigator Award, the 1st Asian Cardiovascular Symposium, Basic Cardiovascular Sciences-American Heart Association, Boston, Massachusetts, 7/29/2019 – 8/1/2019
    • Department of Defense PRMRP Discovery Award 9/1/2020 – 8/31/2022
Thao Ho receiving 1st APSA Award
Thao Ho - 1st APSA Award
  • Summer undergraduate student Thao Ho won the 1st Place Program Award from the Institute of Biosciences and Technology Biotechnology Summer Research Program, August 2019.
  • Ho also won the 1st Place in undergraduate poster competition at the American Physician Scientist Association Southern Regional Meeting, September 7, 2019.
Weijia Luo won 1st place of Young Investigator Award - American Heart Association
Weijia Luo - 1st Place American Heart Association-Basic Cardiovascular Sciences 2019
  • Postdoc Weijia Luo, Ph.D., presented her exosome study at the 1st Asian Cardiovascular Symposium of the American Heart Association - Basic Cardiovascular Sciences in Boston, Massachusetts, July 29, 2019 – August 1, 2019.
  • Luo won 1st place in the Young Investigator Award category at the Asian Cardiovascular Symposium of the American Heart Association, where young scientists from Asian countries joined to compete.

Selected Publications

  1. Dai, Y., Luo, W., Yue, X., Ma, W., Wang, J., & Chang, J. (2020). Identification and characterization of a new isoform of small GTPase RhoE. Communications Biology, 3(572). https://www.nature.com/articles/s42003-020-01295-4#citeas

  2. Luo, W., Dai, Y., Chen, Z., Yue, X., Andrade-Powell, K. C., & Chang, J. (2020). Spatial and temporal tracking of cardiac exosomes in mouse using a nano-luciferase-CD63 fusion protein. Communications Biology, 3(1), 114. https://pubmed.ncbi.nlm.nih.gov/32157172/

  3. Dai, Y., Song, J., Li, W., Yang, T., Yue, X., Lin, X., Yang, X., Luo, W., Guo, J., Wang, X., Lai, S., Andrade, K. C., & Chang, J. (2019). RhoE fine-tunes inflammatory response in myocardial infarction. Circulation, 139(9). https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.118.033700

  4. Dai, Y., Luo, W., & Chang, J. (2018). Rho kinase signaling and cardiac physiology. Current Opinion in Physiology, 1, 14-20. https://www.ncbi.nlm.nih.gov/pubmed/29527586

  5. Cao, J., Yu, Y., Zhang, Z., Chen, X., Hu, Z., Tong, Q., Chang, J., Feng, X.-H., & Lin, X. (2018). SCP4 promotes gluconeogenesis through FoxO1/3a dephosphorylation. Diabetes. https://www.ncbi.nlm.nih.gov/pubmed/28851713

  6. Yi, X., Tao, Y., Lin, X., Dai, Y., Yang, T., Yue, X., Jiang, X., Li, Y., Jiang, D.-S., Andrade, K. C., & Chang, J. (2017). Histone methyltransferase Setd2 is critical for the proliferation and differentiation of myoblasts. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. https://www.ncbi.nlm.nih.gov/pubmed/28130125

  7. Yue, X., Lin, X., Yang, T., Yang, X., Yi, X., Jiang, X., Li, X., Guo, J., Li, T., Dai, Y., Shi, J., Wei, L., Youker, K. A., Torre-Amione, G., Yu, Y., Andrade, K. C., & Chang, J. (2016). Rnd3/RhoE modulates HIF1α and regulates responsive cardiac angiogenesis. Hypertension. https://www.ncbi.nlm.nih.gov/pubmed/26781283

  8. Yang, X., Wang, T., Li, L., Lin, X., Yue, X., Wang, Q., Wang, G., Fu, Q., Ai, X., Chiang, D. Y., Miyake, C. Y., Wehrens, X. H. T., & Chang, J. (2015). Genetic deletion of Rnd3/RhoE results in mouse heart calcium leakage through upregulation of protein kinase A signaling. Circulation Research, 116(1), e1-e10. https://www.ncbi.nlm.nih.gov/pubmed/25348166

  9. Yue, X., Yang, X., Lin, X., Yang, T., Yi, X., Dai, Y., Guo, J., Li, T., Shi, J., Wei, L., Fan, G.-C., Chen, C., & Chang, J. (2014). Rnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure. Cell Death & Disease, 5, e1284. https://www.ncbi.nlm.nih.gov/pubmed/24901055

  10. Lin, X., Liu, B., Yang, X., Yue, X., & Chang, J. (2013). Rnd3 deficiency results in aqueductal stenosis contributing to hydrocephalus through upregulation of Notch signaling. Proceedings of the National Academy of Sciences, 110(20), 8236-8241. https://www.ncbi.nlm.nih.gov/pubmed/23630292

  11. Yang, X., Li, Q., Lin, X., Ma, Y., Yue, X., Tao, Z., Wang, F., Mckeehan, W. L., Wei, L., Schwartz, R. J., & Chang, J. (2012). Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. The FASEB Journal. https://www.ncbi.nlm.nih.gov/pubmed/22278938

  12. Lin, X., Yang, X., Li, Q., Ma, Y., Cui, S., He, D., Lin, X., Schwartz, R. J., & Chang, J. (2012). Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway. Molecular and Cellular Biology, 32(2), 297-308. https://www.ncbi.nlm.nih.gov/pubmed/22106411

Complete List of Publications

https://www.ncbi.nlm.nih.gov/myncbi/jiang.chang.1/bibliography/public/