Jun Xia, PHD
Assistant Professor
Contact
Center for Genomic and Precision Medicine
2121 W. Holcombe Blvd.
Room 720E/F, Lab 721
Houston,
TX
77030
junxia@tamu.edu
Phone: 713.677.7434
Biography
Dr. Jun Xia joins the IBT as an Assistant Professor in the Center for Genomic and Precision Medicine (CGPM). He received his bachelor’s degree in biology/biological sciences from Zhejiang University in Hangzhou, China, and his PhD in Cell/Cellular and Molecular Biology from Baylor College of Medicine in Houston. He has come back to Texas from his position as an Assistant Professor at Creighton University in Omaha, Nebraska.
Dr. Xia’s research focuses on surgical cancers genomics, endogenous DNA damage and toxicogenomics. He has published numerous peer-reviewed articles in esteemed journals such as Nature Genetics, Cell, NPJ Precision Oncology, and Science Advances. Dr. Xia has been honored with the K99/R00 Pathway to Independence Award by NIH/NIEHS, the 2020 STAT News Wunderkinds Award, and the 2022 EMGS Young Scientist Award.
Representative Publications
Xia J*, Chiu L-Y*, Nehring RB, Bravo Núñez MA, Mei Q, Perez M, Zhai Y, Fitzgerald DM, Pribis JP, Wang Y, Hu CW, Powell RT, LaBonte SA, Jalali Ali, Matadamas Guzmán ML, Lentzsch AM, Szafran AT, Joshi MC, Richters M, Gibson JL, Frisch RL, Hastings PJ, Bates D, Queitsch C, Hilsenbeck SG, Coarfa C, Hu JC, Siegele DA, Scott KL, Liang H, Mancini MA, Herman C†, Miller KM† and Rosenberg SM†. 2019. Bacteria-to-human protein networks reveal origins of endogenous DNA damage. Cell 176, 127-143 PMID: 30633903 PMCID: PMC6344048 *equal contributions, †co-corresponding.
Byun J*, Han Y*, Li Y*, Xia J*, Long E* et al. Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer. Nat Genet. 2022 Aug;54(8):1167-1177. PMID: 35915169; PMCID: PMC9373844. *equal contributions.
Liu, Jingjing, Jullian O. Perren, Cody M. Rogers, Sadeieh Nimer, Alice X. Wen, Jennifer A. Halliday, Devon M. Fitzgerald, Qian Meir, Ralf B. Nehring, Mary Crum, Stanislave G. Kozmin, Jun Xia et al. "Endogenous DNA damage at sites of terminated transcripts." Nature (2025): 1-9.
Liu Y*, Xia J*, …, Amos CI. 2021. Rare deleterious germline variants and risk of lung cancer. npj Precision Oncology 5(1), PMID: 33594163 PMCID: PMC7887261. *equal contributions.
Lesley B Conrad*, Shiwei Yin, Bingru Feng, LaShalle King, Brenna Hobson, Katelyn Andersen, John Coté, Robin Farias-Eisner, Jun Xia*, Yusi Fu* Dynamic uterine microenvironment drives endometrial adenocarcinoma carcinogenesis and progression. bioRxiv 2025.08.11.669782; doi: https://doi.org/10.1101/2025.08.11.669782 * co-corresponding.
Fu Y†, Agrawal S, Snyder DR, Yin S, Zhong N, Grunkemeyer JA, Dietz N, Corlett R, Hansen LA, Al-Refaie W, Nandipati KC†, Xia J†. (2024). Transcriptomic changes and gene fusions during the progression from Barrett’s esophagus to esophageal adenocarcinoma. Biomarker research, 12(1), 78. PMID:39113153; PMCID: PMC9373844. †Co-corresponding.
Xia J*, Chen LT*, Mei Q*, Ma CH, Halliday JA, Lin HY, Magnan D, Pribis JP, Fitzgerald DM, Hamilton HM, Richters M, Nehring RB, Shen X, Li L, Bates D, Hastings PJ, Herman C, Jayaram M, Rosenberg SM. 2016. Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Sci Adv 2, e1601605. PMID:28090586 PMCID: PMC5222578. *equal contributions.