Paul J. Derry

Biography

Education and Training

• Bachelor of Arts in Chemistry, Austin College, Sherman, TX, 2011
• Master of Arts in Chemistry, Rice University, Houston, TX, 2013
• Doctor of Philosophy in Chemistry, Rice University, Houston, TX, 2016
• Postdoctoral Research Fellow, Department of Neurology, Baylor College of Medicine, Houston, TX, 2016-2017
• NIH T32 Postdoctoral Research Fellow, Department of Internal Medicine and Center for Translational Research on Inflammatory Disease, Baylor College of Medicine, Houston, TX, 2017-2018

Research Interests

My research is focused on three key areas. First, the redox properties of colloidal carbon nanomaterials derived from materials other than graphene oxide are not well-established. My effort here is to better understand how these materials interact with other reactive species and how they may be applied therapeutically in neurological disease and injury. Second, I study how nanomaterial synthesis alters the performance of carbon nanomaterials in vitro in models of oxidative stress. Lastly, I am interested in understanding how carbon nanomaterials interact with the mitochondria and if they can be used therapeutically in instances of mitochondrial disease. These projects are part of a larger collaborative effort to design therapeutic carbon nanomaterials from labs throughout the Texas Medical Center: the Tour Lab at Rice University, the Tsai Lab at University of Texas Health Science Center, and the Robertson Lab at Baylor College of Medicine.

Selected Publications

• Derry, P. J., Nilewski, L. G., Sikkema, W. K. A., Mendoza, K., Jalilov, A., Berka, V., Dalmeida, W. V., Tsai, A-L., Tour, J. M., Kent, T. A. (2019). Catalytic oxidation and reduction reactions of hydrophilic carbon clusters with NADH and cytochrome C: features of an electron transport nanozyme. Nanoscale. 11(22), 10791-10807.
• Nilewski, L., Mendoza, K. Jalilov, A. S., Berka, V., Wu, G., Sikkema, W. K. A., Metzger, A., Ye, R., Zhang, R., Luong, D. X., Wang, T., McHugh, E. A., Derry, P. J., Samuel, E. L., Kent, T. A., Tour, J. M. (2019). Highly Oxidized Graphene Quantum Dots from Coal as Efficient Antioxidants. ACS Appl. Mater. Interfaces. 11(18), 16815-16821.
• Mendoza, K.†, Derry, P. J.†, Cherian, L., Garcia, R., Nilewski, L., Goodman, C. J., Mbye, L., Tour, J. M., Kent, T. A. (2018). Improved outcome with a catalytic carbon nano-antioxidant in experimental traumatic brain injury complicated by hypotension. J. Neurotrauma. 36(13), 2139-2146.
• Fabian, R. H.†, Derry, P. J.†, Rea, H. C., Samuel, E. L., Nilewski, L. G., Sikkema, K. A., Mandava, P., Tsai, A-L., Mendoza, K., Berka, V., Tour, J. M., Kent, T. A. (2018) Efficacy of Novel Carbon Nanoparticle Antioxidant Therapy in a Severe Model of Reversible Middle Cerebral Artery Stroke in Acutely Hyperglycemic Rats. Front. Neurol. 9, 199. 

A complete listing can be found here: https://scholar.google.com/citations?user=hT1EgAgAAAAJ