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Selected Publications

Selected Publications

  • Myzak M, Karplus PA, Chung FL, Dashwood RH (2004) A novel mechanism of chemoprotection by sulforaphane: Inhibition of histone deacetylase. Cancer Res 64:5767-74.
  • Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH (2011) Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly. Mol Cancer 10:68. PMC3127849 [Highly accessed]
  • Rajendran P, Ho E, Williams DE, Dashwood RH (2011) Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. Clin Epigenetics 3:4. PMC3255482. [Highly accessed]
  • Rajendran P, Dashwood WM, Li L, Kang Y, Kim E, Johnson G, Fischer KA, Löhr CV, Williams DE, Ho E, Yamamoto M, Lieberman DA, Dashwood RH (2015) Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon. Clin Epigenetics 7:102. PMC4575421 [highly accessed]
  • Ertem F, Rajendran P, Dashwood WM, Raju GS, Dashwood RH (2016) Development of a murine colonoscopic polypectomy model. Gastrointest Endosc 83:1272-6. PMC4875801
  • Ertem FU, Zhang W, Chang K, Dashwood WM, Rajendran P, Sun D, Abudayyeh A, Vilar E, Abdelrahim M, Dashwood RH (2017) Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam. Int J Cancer 140:460-468.
  • Johnson GS, Li J, Beaver LM, Dashwood WM, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH (2017) A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a co-activator of NQO1 in sulforaphane-treated colon cancer cells. Mol Nutr Food Res 61:in press. PMC5380536 [Front Cover]
  • Wang R, Chen Y-S, Dashwood WM, Li Q, Löhr CV, Fischer KA, Ho E, Williams DE, Dashwood RH (2017) Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors. Mol Carcinogen 56:1733-1742. PMC5479755
  • Chen Y-S, Wang R, Dashwood WM, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH (2017) A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat. Arch Toxicol 91:3415-25. PMC5836314
  • Zhang J, Tan P, Guo L, Gong J, Ma J, Li J, Lee M, Fang S, Jing J, Johnson S, Sun D, Cao WM, Dashwood R, Han L, Zhou Y, Dong WG, Huang Y (2019) p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance. Oncogene 38:1905-19. PMC6419514
  • Rajendran P, Johnson GS, Li L, Chen YS, Dashwood WM, Nguyen N, Ulusan AM, Ertem FU, Zhang M, Li J, Sun D, Huang Y, Wang S, Cheung HCE, Lieberman DA, Beaver LM, Ho E, Bedford MT, Chang K, Vilar E, Dashwood RH (2019) Acetylation of CCAR2 establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition. Cancer Res 79:918-927. PMC6397680

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